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What does it do?

Varenicline is used to help you stop smoking.

Before you start

  • Tell your doctor if you have kidney, heart or a mental health problem, or if you have ever had a seizure.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take varenicline regularly as directed with a glass of water.
Take as part of a quit smoking plan from a health professional.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Suicidal thoughts, mood changes, unusual behaviour or thinking, agitation

Tell your doctor immediately

Headache, tiredness or weakness

Trouble sleeping, strange dreams

Dry mouth, changes in taste, change of appetite

Nausea, vomiting, indigestion, abdominal pain, farting, constipation

Skin rash

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.


This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. March 2023

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed