Clozapine is used to treat and prevent schizophrenia. It is also sometimes used for other conditions.
Take clozapine regularly as directed with a glass of water.
Measure clozapine liquid carefully with an oral syringe or measuring spoon. Shake the bottle well (for 90 seconds when you first start the bottle and then 10 seconds every other time) before measuring each dose.
Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.
If you miss more than two days in a row, talk to your doctor before you take any more. You will need to start again at a lower dose with weekly blood tests.
Some medicines available without a prescription may react with clozapine including:
Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort, kava) or recreational drugs.
|Side Effects||Recommended action|
Increased risk of infection - symptoms may include: fever, chills, sore throat, aches and pains, tiredness, pain when peeing, mouth ulcers
Feeling restless, strange or uncontrolled movements, tremor, stiffness
Fast or irregular heartbeat, chest pain, fainting
Symptoms of a blood clot including: sudden shortness of breath, swelling or pain in one leg
Prolonged erection (longer than four hours)
|Tell your doctor immediately|
|Tell your doctor|
Drowsiness, dizziness, weakness, headache, anxiety, blurred vision
More saliva than usual, drooling
Peeing when you don’t want to, bed-wetting, trouble peeing
Less interest in sex, impotence
|Tell your doctor if troublesome|
If you notice any other effects, discuss them with your doctor or pharmacist.
This leaflet contains important, but not all, information about this medicine.
Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. January 2020
For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?
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My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.
For more information about the sheets, see: What does a My Medicines sheet cover?
My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed