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What does it do?

Buspirone is used to treat and prevent anxiety. It is also sometimes used for other conditions.

How should you take it?

Take buspirone regularly as directed with a glass of water. You can take buspirone with or without food, but take it the same way each time.

What if you forget a dose?

Take the missed dose as soon as you remember. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with buspirone including:

  • some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)
  • cold and flu medicines containing dextromethorphan (e.g. Robitussin Dry Cough Forte®)
  • prochlorperazine
  • fluconazole (e.g. Diflucan®) or miconazole (e.g. Daktarin Oral Gel®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort, valerian) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Muscle twitching or shaking you can’t control, confusion, heavy sweating, fever

Tell your doctor immediately

Nervousness

Tingling or numbness

Tell your doctor

Dizziness, drowsiness, tiredness, weakness, trouble sleeping, strange dreams, headache, blurred vision

Stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have liver or kidney problems, Parkinson’s disease or if you have ever had a seizure.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Feelings of anxiety in the first few weeks of therapy are common, but should get better. Discuss with your doctor.
  • Grapefruit, grapefruit juice or sour/Seville oranges may react with buspirone. Discuss with your pharmacist.
  • Buspirone can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?)

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. January 2020

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed