What does it do?

Etravirine is used with other medicines to control HIV.

Before you start

• Tell your doctor if you have ever had hepatitis B or C.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take etravirine regularly as directed with food and a glass of water.
It is very important to take etravirine regularly. If you often forget to take it, it may not work as well.

Do not stop taking etravirine without talking to your doctor first, unless you get a severe skin rash (see side effects).

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with etravirine including:

• orlistat (Xenical®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side Effects	Recommended action
Severe skin rash, skin peeling or blisters	Stop taking and see your doctor immediately
Numbness or tingling of the fingers or toes	Tell your doctor
Skin rash	This can occur in the first few weeks. Rarely, this may be serious. Ring your clinic to check

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

• You will need regular blood tests while taking etravirine to check your viral load.
• As your HIV comes under control, your immune system begins to recover. It may start fighting infections better than before which may make you unwell for a while. Your doctor may call this Immune Reconstitution Inflammatory Syndrome (IRIS).
• Weight gain may occur with treatment for HIV. Discuss this with your health professional.