Valproate sodium is used to treat and prevent seizures. Sometimes it is used for other conditions such as bipolar disorder.
Take valproate sodium regularly as directed with food and a glass of water.
Enteric coated (EC) 200 mg and 500 mg tablet: Swallow whole – do not crush or chew.
100 mg tablet: You can crush these if you need to.
Liquid: Measure carefully with an oral syringe or measuring spoon. Shake the bottle well before measuring each dose.
Take the missed dose as soon as possible and continue as directed.
Some medicines available without a prescription may react with valproate sodium including:
Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. ginkgo) or recreational drugs (e.g. ecstasy).
|Side Effects||Recommended action|
Skin rash, skin peeling or blisters
|Stop taking and see your doctor immediately|
Severe stomach pain, nausea
Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain
Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding
|Tell your doctor immediately|
Confusion, drowsiness or weakness
Loss of co-ordination/walking or handwriting problems, tremor
Changes in vision, unusual eye movements
Hearing loss, ringing in the ears
|Tell your doctor|
Swollen feet or legs
Hair loss or thinning
Changes in periods
Change of appetite or weight
Diarrhoea, stomach upset
|Tell your doctor if troublesome|
If you notice any other effects, discuss them with your doctor or pharmacist.
This leaflet contains important, but not all, information about this medicine.
Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. March 2023
For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?
Te Reo Māori information sheets supported by Health Quality and Safety Commission New Zealand
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My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.
For more information about the sheets, see: What does a My Medicines sheet cover?
My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed