What does it do?

Ticagrelor is used to prevent clots in your blood. It reduces your risk of having a heart attack.

How should you take it?

Take ticagrelor every morning and evening with a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with ticagrelor including:

• anti-inflammatories, such as diclofenac (e.g. Voltaren®), ibuprofen (e.g. Nurofen®), or aspirin (e.g. Disprin®, in doses used for pain relief). These can also be found in some cold and flu medicines (e.g. Nurofen Cold and Flu®).

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side Effects	Recommended action
Easy/unusual bruising or bleeding Coughing or vomiting of blood, vomit that looks like coffee grounds Nose bleeds Red or dark brown urine, red or black bowel motions Chest pain, trouble breathing Headache, dizziness, changes in vision or speech	Tell your doctor immediately
Short of breath Tiredness, pale skin	Tell your doctor
Stomach upset	Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

• Tell your doctor if you have lung, liver or bleeding problems.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• It is important to tell anyone who gives you medical or dental treatment (e.g. doctor, dentist, pharmacist or podiatrist) that you are taking ticagrelor.
• Grapefruit, grapefruit juice or sour/Seville oranges may react with ticagrelor. Discuss with your pharmacist.