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What does it do?

Amantadine is used to treat and prevent the symptoms of Parkinson’s disease and sometimes other conditions.

How should you take it?

Take amantadine regularly as directed with a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with amantadine including:

  • anti-nausea medicines (e.g. Buccastem®, Scopoderm®, Sea-legs®)
  • antihistamines (also found in anti-allergy and cold/flu medicines)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. belladonna) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Fever, sore throat, tiredness, aches and pains

Hallucinations, unusual behaviour or thinking

Fast or irregular heartbeat

Eye pain

Tell your doctor immediately

Swollen feet or legs, short of breath

Skin rash or discolouration

Low mood, nervousness, confusion, anxiety

Trouble peeing

Tell your doctor

Trouble sleeping, drowsiness, strange dreams

Dizziness, headache, tiredness or weakness

Constipation, vomiting, loss of appetite

Dry mouth, dry nose

Blurred vision, eyes sensitive to light


Tell your doctor if troublesome


Take with food and tell your doctor if symptoms persist

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart, blood pressure, kidney, stomach, bowel or mental health problems (such as depression).
  • Tell your doctor if you have trouble peeing, glaucoma, tardive dyskinesia, a chronic muscle condition (e.g. myasthenia gravis), eczema or have ever had a seizure.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Amantadine may make you dizzy or sleepy and make it dangerous to drive, operate machinery or do other activities that require you to be alert. Limit alcohol intake because it can increase these effects.
  • Do not stop taking amantadine suddenly without talking to your doctor first. Your doctor may reduce the dose gradually.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. March 2018

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed