What does it do?

Alprazolam is used to treat anxiety. It is also sometimes used for other conditions.

Before you start

• Tell your doctor if you have liver problems, sleep apnoea, or a head injury.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take alprazolam as directed with a glass of water.

What if you forget a dose?

Take the missed dose if you remember on the same day. If not, skip the dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with alprazolam including:

• some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)
• fluconazole (e.g. Diflucan®) or miconazole (e.g. Daktarin Oral Gel®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort, valerian) or recreational drugs.

What side effects might you notice?

Side Effects	Recommended action
Slow or shallow breathing, hard to wake up Trouble with speech or swallowing	Tell your doctor immediately
Mood changes, agitation, unusual behaviour or thinking, loss of coordination, confusion, memory loss, trouble concentrating Muscle weakness	Tell your doctor
Drowsiness, tiredness, dizziness, headache, changes in vision Dry mouth, stomach upset Less interest in sex, trouble peeing	Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

• Alprazolam can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?)
• If you still feel sleepy the next day, do not drive or operate machinery.
• Alprazolam may be addictive with long-term use.
• If you have been taking alprazolam regularly for a long time, do not stop taking it suddenly without talking to your doctor.
• Sleep problems commonly occur when alprazolam is stopped. It may take several weeks for these to improve.
• Caffeine-containing drinks (e.g. coffee, cola, tea) may reduce the effect of alprazolam. Discuss with your doctor.