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NZ Formulary

Glecaprevir and pibrentasvir

glek-a-pre-vir and pi-brent-as-vir

What does it do?

Glecaprevir and pibrentasvir is used to treat Hepatitis C virus infection.

Before you start

  • Tell your doctor if you have ever had hepatitis B.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take glecaprevir and pibrentasvir as directed with food and a glass of water. It is important to take it regularly. If you often forget to take it, it may not work as well. Keep taking it until the course is finished. Swallow the tablets whole, do not crush or chew them.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Nausea

Headache

Tiredness or weakness

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Do not stop taking glecaprevir and pibrentasvir without talking to your doctor first.

This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. March 2023

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed