What does it do?

Glibenclamide is used to treat diabetes. It lowers blood glucose by increasing the amount of insulin made by your body.

Before you start

• Tell your doctor if you have kidney problems, or G6PD deficiency.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take glibenclamide regularly as directed with a glass of water, preferably at the start of a meal.

What if you forget a dose?

If you miss a dose of glibenclamide do not take it later. Skip the missed dose and continue as directed. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with glibenclamide including:

• miconazole oral gel (e.g. Daktarin Oral Gel®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side Effects	Recommended action
Low blood glucose (hypo): symptoms may include sweating, trembling, feeling anxious or irritable	Drink or eat something sweet. Tell your health professional if this happens a lot or is severe.
Skin rash, itching	Tell your doctor
Stomach upset	Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

• If you are unwell, follow your diabetes sick-day plan, or talk to your health professional.
• Check your blood glucose level as directed by your health professional.
• You will need a regular blood test (HbA1c) to check how your diabetes is controlled.
• Alcohol may change your blood glucose levels and make you more likely to have a hypo. It may also mask your warning signs of low blood glucose. See Alcohol and Diabetes.
• Check your blood glucose levels before driving. Do not drive if you are having a hypo as low blood glucose could make driving unsafe. See Driving with diabetes