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What does it do?

Amantadine is used to treat Parkinson’s disease and sometimes other conditions.

Before you start

  • Tell your doctor if you have kidney or mental health problems, heart failure, angle-closure glaucoma, or have ever had a seizure.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take amantadine regularly as directed with a glass of water. You can take it with or without food.

Do not stop taking amantadine suddenly without talking to your doctor first. Your doctor may reduce the dose gradually.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Reduced number of blood cells that fight infections in your body - symptoms include: fever, chills, sore throat or generally feeling unwell

Tell your doctor immediately

Trouble thinking clearly or concentrating

Seeing, hearing or feeling things that aren’t really there

Unusual urges (e.g. gambling, eating, spending, sex)

Swollen feet or legs, short of breath

Tell your doctor

Dizziness

Constipation

Dry mouth

Net-like red, blue or purple skin patches

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Amantadine can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. See Are you safe to drive?

This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. February 2026

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed