NZ Formulary

Levetiracetam

lev-ee-tye-ra-se-tam

What does it do?

Levetiracetam is used to treat and prevent seizures.

Before you start

  • Tell your doctor if you have kidney problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take levetiracetam regularly as directed. You can take it with or without food.
Tablet: Take with a glass of water.
Liquid: Measure carefully with an oral syringe or measuring spoon. You can mix the liquid in some water.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with levetiracetam including:

  • some antihistamines, such as chlorphenamine, hyoscine, meclozine and promethazine. These can be in medicines for allergies, nausea and colds.

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. ginkgo) or recreational drugs (e.g. ecstasy).

What side effects might you notice?

Side EffectsRecommended action

Skin rash, skin peeling or blisters

Stop taking and see your doctor immediately

Suicidal thoughts

Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding

Tell your doctor immediately

Irritability, mood changes, nervousness

Tell your doctor

Dizziness, drowsiness, tiredness or weakness

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Levetiracetam can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?)
  • Do not stop taking levetiracetam without talking to your doctor first, unless you have a skin rash (see Side Effects).