What does it do?

Pioglitazone is used to treat diabetes by lowering blood sugar.

Before you start

  • Tell your doctor if you have heart problems, or have ever had bladder cancer.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take pioglitazone regularly as directed with a glass of water. You can take it with or without food.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with pioglitazone including:

  • anti-inflammatories, such as diclofenac (e.g. Voltaren®) or ibuprofen (e.g. Nurofen®). These can also be found in some cold and flu medicines (e.g. Nurofen Cold and Flu®).

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Trouble breathing

Tell your doctor immediately

Swollen feet or legs, short of breath

Tiredness, dizziness, pale skin

Changes in vision

Bloody pee

Tell your doctor

Weight gain


Sore throat, cough, runny nose, sneezing

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Test your blood sugar as directed by your health professional.
  • Pioglitazone can weaken your bones. You may need tests to check for this before you start.