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What does it do?

Voriconazole is used to treat and prevent fungal infections.

How should you take it?

Take voriconazole regularly as directed. Keep taking it until the course is finished, even if you start to feel better. Take it on an empty stomach - one hour before or two hours after food.
Tablets: Take with a glass of water.
Liquid: Measure carefully with an oral syringe or measuring spoon. Shake the bottle well before measuring each dose.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with voriconazole including:

  • sildenafil (e.g. Viagra®) or similar medicines
  • anti-inflammatories, such as diclofenac (e.g. Voltaren®) or ibuprofen (e.g. Nurofen®). These can also be found in some cold and flu medicines (e.g. Nurofen Cold and Flu®).

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of allergy including: skin rash, itching, swelling, trouble breathing

Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Symptoms of a fast or irregular heartbeat including: fluttering, pounding or pain in your chest, dizziness or fainting

Severe stomach pain, nausea

Tell your doctor immediately

Hallucinations, confusion

Changes in vision

Tell your doctor

Swollen feet or legs

Headache

Stomach upset

More sensitive to sunlight (sunburn or rash)

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have liver, kidney or heart problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Protect yourself from too much sunlight while being treated with voriconazole. Always cover up and apply a thick layer of broad spectrum sunscreen (at least SPF 30) when outside. Do not use sunbeds.
  • Due to changes in vision that can happen with voriconazole, take extra care when driving or operating machinery, especially at night.
  • You will need regular blood tests while taking voriconazole to check if it is causing problems with your liver or kidneys. You may also need blood tests to check how much voriconazole is in your blood.
  • Your doctor may do a heart test (ECG) before you start and while you are taking voriconazole.
  • If you take voriconazole for a long time, it may cause bone problems. Discuss this with your doctor.
  • Store voriconazole liquid as directed. Once the course is finished, take any leftover liquid back to your pharmacy.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. May 2022

For more general information about this sheet annd its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed