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What does it do?

Midodrine is used to treat and prevent low blood pressure.

How should you take it?

Take midodrine as directed with a glass of water. Do not take within four hours of going to bed.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with midodrine including:

  • some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)
  • prochlorperazine
  • caffeine (No-Doz®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. guarana) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Trouble peeing

Blurred vision, eye pain

Tell your doctor

Flushing, goosebumps, chills

Tingling or numbness

Peeing more often

Nausea, indigestion, dry mouth, mouth ulcers

Tell your doctor if troublesome

Fast heartbeat

Pounding in ears, headache

Tell your doctor if troublesome - sleep with your head raised

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart, kidney, liver, thyroid or bladder problems, or have glaucoma, or have had a stroke or ‘mini-stroke’.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Caffeine-containing beverages (eg coffee, cola) may alter the effectiveness of midodrine - discuss with your doctor.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. March 2019

For more general information about this sheet annd its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed