Leflunomide is used to treat some types of arthritis. It may be used alone or with other medicines.
Take leflunomide regularly as directed with a glass of water. Do not break or crush the tablets.
Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.
Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. activated charcoal, St John's wort) or recreational drugs.
|Side Effects||Recommended action|
Severe skin rash, skin peeling or blisters
|Stop taking and see your doctor immediately|
Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding
Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain
Short of breath, persistent dry cough
|Tell your doctor immediately|
Pain, sores, or redness in mouth or on lips
|Tell your doctor|
Hair loss or thinning
Joint or muscle aches or pains, numbness or tingling of the fingers or toes
Diarrhoea, nausea, loss of appetite, weight loss
|Tell your doctor if troublesome|
If you notice any other effects, discuss them with your doctor or pharmacist.
This leaflet contains important, but not all, information about this medicine.
Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. September 2021
For more general information about this sheet annd its contents, see: What does a My Medicines sheet cover?
Click on buttons to copy web addresses for this leaflet:
If your browser does not automatically copy these links use its copy command instead.
My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.
For more information about the sheets, see: What does a My Medicines sheet cover?
My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed