What does it do?

Propylthiouracil reduces the amount of thyroid hormone made by your thyroid gland.

Before you start

• Tell your doctor if you have liver problems.
• Tell your doctor if you are pregnant or breastfeeding. If you are planning to get pregnant or find that you are, discuss this with your doctor. Use reliable contraception while taking propylthiouracil.
• You will need a blood test to check your liver and your blood cells.

How should you take it?

Take propylthiouracil regularly as directed with a glass of water. You can take it with or without food.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with propylthiouracil including:

• iodine supplements

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. kelp) or recreational drugs.

What side effects might you notice?

Side Effects	Recommended action
Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain	Tell your doctor immediately
Skin rash	Tell your doctor
Joint, muscle or bone aches and pains	Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

• You will need regular blood tests while you are taking propylthiouracil to make sure you are on the right dose.
• Propylthiouracil is not registered for use in New Zealand. Discuss with your doctor.