Cyclophosphamide is an immunosuppressant medicine used to treat inflammatory conditions such as rheumatoid arthritis and systemic lupus erythematosus (lupus/SLE). It is sometimes used for other conditions.
Take cyclophosphamide regularly as directed, usually in the morning. Take with food and a glass of water. Swallow the tablets whole – do not break, crush or chew.
Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.
Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort, echinacea) or recreational drugs.
|Side Effects||Recommended action|
Symptoms of allergy including: skin rash, itching, swelling, trouble breathing
Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding
Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain
Swollen feet or legs, fast or irregular heartbeat
Short of breath, persistent dry cough
|Tell your doctor immediately|
Bloody or cloudy pee, pain when peeing
|Tell your doctor|
Hair loss or thinning, darkening of skin or fingernails
Changes in periods
Nausea, vomiting, loss of appetite, diarrhoea
|Tell your doctor if troublesome|
If you notice any other effects, discuss them with your doctor or pharmacist.
This leaflet contains important, but not all, information about this medicine.
Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. March 2023
For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?
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My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.
For more information about the sheets, see: What does a My Medicines sheet cover?
My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed