skip to main content

What does it do?

Topiramate is used to treat and prevent seizures. Sometimes it is used for other conditions, such as preventing migraines.

Before you start

  • Tell your doctor if you have kidney problems or angle-closure glaucoma.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take topiramate regularly as directed with a glass of water. You can take it with or without food.
Capsule: If you have trouble swallowing you can open the capsule and sprinkle the contents on a small amount of soft food. Swallow the mixture straight away.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with topiramate including:

  • some antihistamines, such as chlorphenamine, hyoscine, meclozine and promethazine. These can be in medicines for allergies, nausea and colds.

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. ginkgo) or recreational drugs (e.g. ecstasy).

What side effects might you notice?

Side EffectsRecommended action

Suicidal thoughts

Blurred vision, eye pain

Tell your doctor immediately

Confusion, loss of co-ordination/walking or handwriting problems, memory problems, trouble concentrating

Mood changes, nervousness

Tingling or numbness, tremor

Lower back pain, pink/red/brown pee (may be a kidney stone)

Tell your doctor

Dizziness, drowsiness, slow or slurred speech


Tiredness or weakness

Dry mouth or throat, changes in taste, loss of appetite, weight loss

Stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Some special diets (e.g. ketogenic) may react with topiramate – talk to your doctor.
  • Topiramate can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?)
  • Topiramate may cause kidney stones. Drinking plenty of water can help to prevent this.
  • Do not stop taking topiramate without talking to your doctor first.

This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. March 2023

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

Web links for this sheet in different formats

Click on buttons to copy web addresses for this leaflet:

If your browser does not automatically copy these links use its copy command instead.

About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed