What does it do?

Posaconazole is used to treat and prevent fungal infections.

Before you start

• Tell your doctor if you have liver, kidney or heart problems.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Your doctor may do a heart test (ECG) before you start and while you are taking posaconazole.

How should you take it?

Take posaconazole regularly with food as directed. Measure the liquid carefully with an oral syringe or measuring spoon. Shake the bottle well before measuring each dose. Keep taking it until the course is finished, even when you start to feel better.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with posaconazole including:

• sildenafil (e.g. Viagra®) or similar medicines
• omeprazole (e.g. Losec®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side Effects	Recommended action
Symptoms of allergy including: skin rash, itching, swelling, trouble breathing Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain Fainting	Tell your doctor immediately
Headache Stomach upset	Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

• You will need regular blood tests while taking posaconazole to check if it is causing problems with your liver or kidneys. You may also need blood tests to check how much posaconazole is in your blood.