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What does it do?

Itraconazole is used to treat and prevent fungal infections.

Before you start

  • Tell your doctor if you have liver, kidney or heart problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Your doctor may do a heart test (ECG) before you start and while you are taking itraconazole.

How should you take it?

Take itraconazole regularly as directed. Keep taking it until the course is finished, even if you start to feel better.
Capsule: Take with food and a glass of water. Swallow them whole.
Liquid: Measure carefully with an oral syringe or measuring spoon. Take it on an empty stomach - one hour before or two hours after food.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with itraconazole including:

  • indigestion medicines such as antacids (e.g. Mylanta®, Gaviscon®), and omeprazole (Losec®)
  • sildenafil (e.g. Viagra®) or similar medicines

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of allergy including: skin rash, itching, swelling, trouble breathing

Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain


Severe stomach pain, nausea

Tell your doctor immediately

Swollen feet or legs, short of breath

Tell your doctor

Headache, dizziness

Stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Grapefruit, grapefruit juice or sour/Seville oranges may react with itraconazole. Discuss with your pharmacist.
  • Do not take indigestion remedies within 2 hours of itraconazole.
  • You will need regular blood tests while taking itraconazole to check if it is causing problems with your liver. You may also need blood tests to check how much itraconazole is in your blood.
  • Itraconazole liquid expires 3 months after you first open the bottle. If you have any liquid leftover after 3 months, take it back to your pharmacy.

This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. March 2023

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed