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What does it do?

Itraconazole is used to treat and prevent fungal infections.

How should you take it?

Take itraconazole regularly as directed. Keep taking it until the course is finished, even if you start to feel better.
Take the capsules with food and a glass of water. Swallow them whole.
Measure the liquid carefully with an oral syringe or measuring spoon. Take it on an empty stomach - one hour before or two hours after food.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with itraconazole including:

  • calcium supplements (e.g. Calci-Tab®)
  • indigestion medicines such as antacids (e.g. Mylanta®, Gaviscon®), ranitidine (e.g. Zantac®) and omeprazole (Losec®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of allergy including: skin rash, itching, swelling, trouble breathing

Fever, sore throat, chills, aches and pains, tiredness

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Change in heartbeat, chest pain, fainting

Tell your doctor immediately

Swollen feet or legs, short of breath

Tell your doctor


Nausea, diarrhoea, vomiting, bloating, indigestion

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have liver, kidney or heart problems, or have high cholesterol.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Grapefruit, grapefruit juice or sour/Seville oranges may react with itraconazole. Discuss with your pharmacist.
  • Do not take indigestion remedies or calcium within two hours of taking itraconazole.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. February 2018

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed