NZ Formulary

Amphotericin (injection)

What does it do?

Amphotericin is used to treat and prevent fungal infections.

How is it given?

Amphotericin is given as a slow injection into a vein or central line. Continue the course until it is finished, even if you start to feel better.

What if you forget a dose?

Amphotericin is usually given to you by a health professional. If you miss a dose, contact your health professional as soon as possible.

Can you take other medicines?

Some medicines available without a prescription may react with amphotericin including:

  • fluconazole (e.g. Diflucan®) or miconazole (e.g. Daktarin Oral Gel®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. ginkgo) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Swollen lips, tongue, throat or face, trouble breathing

Rash, redness and pain at injection site

Bloody or cloudy pee, trouble peeing

Tingling or numbness

Chest pain, fast, slow or irregular heartbeat

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Fever, sore throat, tiredness, aches and pains

Easy/unusual bruising or bleeding

Tell your doctor immediately

Chills, headache, flushing, dizziness

Joint or muscle pains, cramps or weakness

Drowsiness, confusion, agitation, lack of energy

Trouble sleeping, hallucinations, low mood

Hair loss or thinning

Loss of appetite, stomach upset

Swollen feet or legs

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have liver, kidney, heart, blood or lung problems; or have diabetes.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.