NZ Formulary

Vigabatrin

vi-ga-ba-trin

What does it do?

Vigabatrin is used to treat and prevent seizures.

How should you take it?

Take vigabatrin regularly as directed with a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with vigabatrin including:

  • anti-nausea medicines (e.g. prochlorperazine, hyoscine (e.g. Scopoderm TTS®), meclozine (e.g. Sea-legs®)
  • some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. ginkgo) or recreational drugs (e.g. ecstasy).

What side effects might you notice?

Side EffectsRecommended action

Suicidal thoughts

Tell your doctor immediately

Changes in vision

Confusion, drowsiness or weakness

Anxiety, irritability, loss of co-ordination/walking or handwriting problems, low mood, memory problems, trouble concentrating, trouble speaking

Tell your doctor

Tiredness, headache, dizziness

Tremor, tingling or numbness, joint, muscle or bone aches and pains

Weight gain, swollen feet or legs

Stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have kidney problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Vigabatrin can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?)
  • You may need regular eye tests while taking vigabatrin. Talk to your doctor.
  • Do not stop taking vigabatrin without talking to your doctor first.