NZ Formulary

Cyproterone

sye-pro-te-rone

What does it do?

Cyproterone blocks the effects of testosterone (a male sex hormone) in the body. In men it is used to treat prostate cancer or reduce sex drive. In women it is used to treat polycystic ovary syndrome, excess body hair, acne, or head hair loss.

How should you take it?

Take cyproterone regularly as directed with a glass of water.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Tell your doctor immediately

Short of breath

Tell your doctor

Sore or enlarged breasts

Hot flushing, sweating

Less body and facial hair

Weight changes

Tiredness or weakness

Less interest in sex, trouble getting or keeping an erection

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart or liver problems, diabetes or depression, or if you have ever had a stroke or blood clot.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Cyproterone can affect fertility in both men and women – discuss with your doctor.
  • Cyproterone may make you dizzy or sleepy and make it dangerous to drive, operate machinery or do other activities that require you to be alert. Limit alcohol intake because it can increase these effects.
  • You will need regular blood tests while taking cyproterone to check if it is causing problems with your liver.