NZ Formulary

Posaconazole (tablet)

poe-sa-kon-a-zole

What does it do?

Posaconazole is used to treat and prevent fungal infections.

Before you start

  • Tell your doctor if you have liver, kidney or heart problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Your doctor may do a heart test (ECG) before you start and while you are taking posaconazole.

How should you take it?

Take posaconazole regularly as directed with a glass of water. Swallow the tablet whole, do not crush or chew it. Keep taking it until the course is finished, even when you start to feel better.

What if you forget a dose?

Take the missed dose as soon as possible and continue as directed.

Can you take other medicines?

Some medicines available without a prescription may react with posaconazole including:

  • sildenafil (e.g. Viagra®) or similar medicines

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of allergy including: skin rash, itching, swelling, trouble breathing

Reduced number of blood cells that fight infections or help your blood to clot - symptoms include: fever, chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Fainting

Tell your doctor immediately

Headache

Stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • You will need regular blood tests while taking posaconazole to check if it is causing problems with your liver or kidneys. You may also need blood tests to check how much posaconazole is in your blood.