NZ Formulary

Allopurinol

al-oh-pure-ih-nol

What does it do?

Allopurinol is used to prevent gout and kidney stones. It reduces the amount of uric acid made in your body.

How should you take it?

Take allopurinol regularly as directed. Take with food and a glass of water.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Skin rash, itching, fever

Stop taking and see your doctor immediately

Trouble peeing

Gout attack

Headache, dizziness, drowsiness

Tell your doctor if troublesome

Stomach upset

Take with food

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have kidney or liver problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Allopurinol can cause kidney stones if you do not drink enough fluid. Discuss with your healthcare professional.
  • Allopurinol can cause a gout attack when you start taking it, so your doctor may prescribe another medicine to prevent this happening. Keep taking allopurinol during a gout attack. Stopping the tablets suddenly is likely to make your gout worse.