NZ Formulary



What does it do?

Amantadine is used to treat Parkinson’s disease and sometimes other conditions.

How should you take it?

Take amantadine regularly as directed with a glass of water.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

Important information continues on next page.

What side effects might you notice?

Side EffectsRecommended action

Increased risk of infection - symptoms may include: fever, chills, sore throat, aches and pains, tiredness, pain when peeing, mouth ulcers


Tell your doctor immediately

Agitation, anxiety, confusion, hallucinations

Unusual urges (e.g. gambling, eating, spending, sex)

Low mood

Unsteadiness, strange or uncontrolled movements

Swollen feet or legs, short of breath

Tell your doctor

Drowsiness, dizziness, trouble sleeping

Constipation, loss of appetite

Dry mouth

Net-like red, blue or purple skin patches

Tell your doctor if troublesome

Lightheaded or dizzy after standing up

Stand up slowly. If it continues, or is severe, tell your doctor


Take with food and tell your doctor if symptoms persist

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart, blood pressure, kidney, stomach, bowel or mental health problems (such as depression).
  • Tell your doctor if you have trouble peeing, glaucoma, tardive dyskinesia, a chronic muscle condition (e.g. myasthenia gravis), eczema or have ever had a seizure.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Amantadine can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?)
  • Do not stop taking amantadine suddenly without talking to your doctor first. Your doctor may reduce the dose gradually.