NZ Formulary

Zuclopenthixol (tablet)

zoo-kloe-pen-thix-ol

What does it do?

Zuclopenthixol is used to treat some mental health problems such as schizophrenia. It is also sometimes used for other conditions.

How should you take it?

Take zuclopenthixol regularly as directed with a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with zuclopenthixol including:

  • some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)
  • anti-nausea medicines (e.g. prochlorperazine, hyoscine (e.g. Scopoderm TTS®), meclozine (e.g. Sea-legs®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort, valerian) or recreational drugs (e.g. cannabis).

Important information continues on next page.

What side effects might you notice?

Side EffectsRecommended action

Fever, stiffness, sweating, confusion

Feeling restless, strange or uncontrolled movements, tremor

Fast or irregular heartbeat, fainting

Symptoms of a blood clot including: sudden shortness of breath, swelling or pain in one leg

Seizures

Prolonged erection (longer than four hours)

Tell your doctor immediately

Dizziness, drowsiness, trouble sleeping

Weight gain

Dry mouth, blurred vision, constipation, trouble peeing

Stomach upset

Changes in periods

Sore or enlarged breasts, breastmilk production

Less interest in sex, impotence

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart, liver, bowel, bladder, prostate or eye (e.g. glaucoma) problems.
  • Tell your doctor if you have diabetes, Parkinson’s disease, have ever had a seizure, blood clot, stroke or ‘mini-stroke’, or if you have experienced strange body movements with another medicine.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Your doctor may do a heart test (ECG) before you start and while you are taking zuclopenthixol.
  • Zuclopenthixol may make you dizzy or sleepy and make it dangerous to drive, operate machinery or do other activities that require you to be alert. Limit alcohol intake because it can increase these effects.
  • Zuclopenthixol reduces your body’s ability to maintain a normal temperature. Be careful of becoming too cold or too hot. When exercising, drink plenty of water.
  • You have an increased risk of getting diabetes while taking zuclopenthixol. Discuss with your doctor.
  • Do not stop taking zuclopenthixol without talking to your doctor first.