skip to main content

What does it do?

Domperidone is used to treat and prevent nausea and vomiting. It is also sometimes used for other conditions.

How should you take it?

Take domperidone as directed with a glass of water.

What if you forget a dose?

Should an occasional dose be missed it need not be taken later.

Can you take other medicines?

Some medicines available without a prescription may react with domperidone including:

  • fluconazole (e.g. Diflucan®)
  • antacids (e.g. Mylanta®) - do not take these within two hours of taking domperidone.

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Fast or irregular heartbeat, fainting

Tell your doctor immediately

Headache

Dry mouth or throat

Diarrhoea

Sore or enlarged breasts, breastmilk production

Irregular periods

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart, bowel, liver or kidney problems, or if you have a pituitary tumour.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Your doctor may do a heart test (ECG) before you start and while you are taking domperidone.
  • Grapefruit, grapefruit juice or sour/Seville oranges may react with domperidone. Discuss with your pharmacist.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. December 2017

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

Web links for this sheet in different formats

Click on buttons to copy web addresses for this leaflet:

If your browser does not automatically copy these links use its copy command instead.

About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed