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What does it do?

Flutamide is used to treat prostate cancer, polycystic ovary syndrome and sometimes other conditions.

How should you take it?

Take flutamide regularly as directed with food and a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with flutamide including:

  • fluconazole (e.g. Diflucan®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort, DHEA) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Fever, sore throat, tiredness, aches and pains

Trouble breathing

Tell your doctor immediately

Trouble sleeping, drowsiness, dizziness, low mood

Sore or enlarged breasts, breastmilk production

Hot flushing, pale skin

Less interest in sex, changes in sexual function

Weight changes, stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have liver or heart problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Protect yourself from too much sunlight while being treated with flutamide. Always cover up and apply a thick layer of broad spectrum sunscreen (at least SPF 30) when outside. Do not use sunbeds.
  • Dark urine must be reported to your doctor immediately. However, a slight change in urine colour to yellow-green appearance is usually harmless.
  • Flutamide is not registered for use in New Zealand. Discuss with your doctor.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. January 2018

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed