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What does it do?

Entacapone is used to treat and prevent the symptoms of Parkinson’s disease.

How should you take it?

Take entacapone regularly as directed with a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with entacapone including:

  • some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)
  • anti-nausea medicines (e.g. Buccastem®, Scopoderm®, Sea-legs®)
  • iron supplements (e.g. Ferro-Tab®) – separate dose by two hours

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Hallucinations

Short of breath, chest pain

Tell your doctor

Drowsiness, trouble sleeping, strange dreams

Dizziness, anxiety

Loss of co-ordination/walking or handwriting problems

Tiredness or weakness

Dry mouth or throat, changes in taste

Stomach upset, diarrhoea, nausea

Sweating

Tell your doctor if troublesome

Change in urine colour (orange)

Harmless unless associated with other symptoms

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have heart, liver or mental health problems.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Entacapone may make you dizzy or sleepy and make it dangerous to drive, operate machinery or do other activities that require you to be alert. Limit alcohol intake because it can increase these effects.
  • Do not stop taking entacapone without talking to your doctor first.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. January 2018

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed