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What does it do?

Selegiline is used to treat and prevent the symptoms of Parkinson’s disease.

How should you take it?

Take selegiline regularly as directed with a glass of water.

What if you forget a dose?

Take the missed dose as soon as possible. If it is close to the time for your next dose, skip the missed dose and carry on as normal. Do not take two doses at the same time.

Can you take other medicines?

Some medicines available without a prescription may react with selegiline including:

  • some antihistamines (may be in anti-allergy, anti-nausea and cough/cold medicines)
  • anti-nausea medicines (e.g. Buccastem®, Scopoderm®, Sea-legs®)
  • cold and flu medicines containing dextromethorphan (e.g. Robitussin Dry Cough Forte®) or phenylephrine (e.g. Sudafed PE®)
  • some migraine medicines, such as sumatriptan (e.g. Sumagran Active®) or zolmitriptan (e.g. Zomig®)

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs (e.g. ecstasy).

What side effects might you notice?

Side EffectsRecommended action

Muscle twitching or shaking you can’t control, confusion, heavy sweating, fever

Fast or irregular heartbeat, chest pain

Seizures

Tell your doctor immediately

Trouble sleeping

Dizziness, headache

Dry mouth, mouth or lip sores

Tell your doctor

Nausea

Take with food

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Tell your doctor if you have liver, heart or stomach problems, or high blood pressure, a mental health condition (e.g. depression) or if you have ever had a seizure.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • High doses of selegiline (more than 10 mg) require some dietary restrictions – ask your pharmacist.
  • Selegiline may cause dizziness and make it dangerous to drive, operate machinery or do other activities that require you to be alert.
  • Feelings of anxiety in the first few weeks of therapy are common, but should get better. Discuss with your doctor.
  • Do not stop taking selegiline without talking to your doctor first.
  • Selegiline is not registered for use in New Zealand. Discuss with your doctor.

This leaflet contains important, but not all, information about this medicine.

Prepared by the PILs Committee at Christchurch Hospital, Canterbury District Health Board, New Zealand. January 2018

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at the Canterbury District Health Board. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed